Imfihlelo engaqhelekanga ye-multiple sclerosis

Imfihlelo engaqhelekanga ye-multiple sclerosis

Ubudlelwane phakathi kwe-multiple sclerosis kunye neemveliso zobisi kuye kwaba yimfihlakalo iminyaka, kodwa uphando olutshanje luveze iinkcukacha zesi siganeko kunye nefuthe laso kwizigulane.

Uphononongo olulungiselelwe ngabaphandi baseJamani abavela kwiiYunivesithi zaseBonn nase-Erlangen-Nuremberg lubonise ukuba iprotheni ethile yobisi lwenkomo inokuvuselela iiseli zokuzivikela ezikhuselekileyo ezibangela umonakalo kwi-neurons kwi-MS.

UStephanie Courten, umphandi oye wasebenza kwesi sifundo ukususela ngo-2018, wachaza ukuba iprotheni ye-casein yisona sizathu salokhu, ngokwento epapashwe yiNew Atlas website.

Kodwa oku kuqwalaselwa kuphela kuqinisekisile ikhonkco, ngelixa abaphandi babenomdla ngakumbi ekufumaneni ukuba iprotheni yobisi inokonakalisa njani i-neurons ehambelana ne-MS.

impendulo engalunganga yomzimba

I-hypothesis kukuba i-casein ibangela impendulo ephosakeleyo ye-immune, oku kuthetha ukuba kufuneka ifane ne-antigens efanayo ekhokelela iiseli ze-immune ukuba zijolise ngokungalunganga kwiiseli zengqondo eziphilileyo, kusho uRitika Chondr, umbhali-mbhali wokufunda.

Wongeze ukuba iimvavanyo ezithelekisa i-casein kunye neemolekyuli ezahlukeneyo ezibalulekileyo kwimveliso ye-myelin, i-fatty coverage ejikeleze iiseli zemithambo-luvo, ikhokelele ekufumaneni i-myelin-binding glycoprotein, ebizwa ngokuba yi-MAG.

Kwakhona, kubonise ukuba le proteni ibonakala ifana ngokuphawulekayo ne-casein ngeendlela ezithile ukuya kwinqanaba lokuba i-casein antibodies yayisebenza ngokuchasene ne-MAG kwizilwanyana zaselabhoratri.

ubisi casein

Abaphandi baye bafumanisa ukuba iiseli zokuzivikela ze-B ezivela kwizigulane ezine-multiple sclerosis zazinomdla kakhulu kwi-casein.

Kwakhona kwaqukumbela ukuba ikhonkco phakathi kweemveliso zobisi kunye neempawu ze-MS kungenxa yeprotheyini ye-casein ebisi ebangela ukunyuka kwamajoni omzimba.

Ezi seli ze-immune zihlasela ngempazamo iiseli ezithile kwingqondo ngenxa yeprotheyini ye-MAG ifana ne-casein, indlela enokuthi ichaphazele kuphela abantu abachasene nobisi.

UCourten uthe uvavanyo lokuzivavanya ngoku luyaphuhliswa apho abantu abachaphazelekayo banokujonga ukuba baphathe izilwa-buhlungu ezihambelanayo, kwaye ubuncinci eli qela kufuneka lizikhwebule kubisi, iyogathi okanye i-cottage cheese.

Ichaphazela ingqondo kwaye akukho nyango

I-Multiple sclerosis sisifo esinokuthi siphazamise ingqondo kunye nentambo yomgogodla (inkqubo ye-nervous central).

Kwi-multiple sclerosis, amajoni omzimba ahlasela i-sheath ekhuselayo (i-myelin) egquma imicu yemithambo-luvo, ibangela iingxaki kunxibelelwano phakathi kwengqondo yakho kunye nomzimba wakho uphela. Esi sifo sinokubangela umonakalo osisigxina we-nerve okanye ukonakala.

Ngelixa alukho unyango olupheleleyo lwe-multiple sclerosis kude kube ngoku. Nangona kunjalo, unyango lunokunceda ngokukhawuleza ukuchacha ekuhlaselweni, ukuguqula indlela yesi sifo kunye nokunyanga iimpawu.