I-Botox yokwelashwa kwezimo zengqondo nezengqondo

Ucwaningo olusha luthola ukuthi imijovo ye-Botox ingasiza ekudambiseni izimpawu zezimo zempilo yengqondo njengokucindezeleka nokukhathazeka. Imijovo ye-BTX botulinum toxin, evame ukubizwa ngokuthi “i-Botox”, isetshenziselwa ikakhulukazi izinqubo zezimonyo, ngoba ibangela ukuphumula kwemisipha, futhi uma isetshenziswa ezindaweni ezithile zobuso, i-Botox inganciphisa imigqa nemibimbi, ngokusho kwe-EuroNews. ucwaningo olushicilelwe kumagazini Imibiko Yesayensi.

"Imisipha Yosizi"

Ukuphumula kwemisipha yobuso kube yisihloko sezifundo eziningi, njengoba ososayensi befuna ukubona ukuthi kungasetshenziswa yini ukukhulula izimpawu zezimo zempilo yengqondo. Ngokuqondile, umbono uwukuthi ungakwazi ukukhomba lokho isazi sokuziphendukela kwemvelo uCharles Darwin esikubiza ngokuthi "imisipha yosizi."

"Wonke lo mkhakha wocwaningo usebenzisa ubuthi be-botulinum njengendlela yokwelapha ukuphazamiseka kwengqondo usekelwe ekucabangeni kwempendulo yobuso," kusho uDkt. Axel Wollmer, uchwepheshe wezengqondo nomcwaningi eNyuvesi yaseSemmelweis eHamburg kanye nomunye wababhali abahamba phambili ocwaningweni. .

Wanezela ukuthi le nkolelo-mbono ihlehlela emuva kuDarwin noWilliam James (owaziwa ngokuthi “uyise” wesazi sokusebenza kwengqondo saseMelika) ekhulwini leshumi nesishiyagalolunye, ebonisa ukuthi ithi isimo sobuso somuntu asigcini nje ngokudlulisela isimo sakhe esingokomzwelo kwabanye, kodwa futhi siyasiveza. kuye ngokwakhe.

Umbono uwukuthi nakuba ezinye izimo zobuso ezinjengokuhwaqabala zibangelwa imizwelo engemihle, isimo sobuso ngokwazo empeleni siqinisa leyo mizwelo embuthanweni ononya.

"Omunye uqinisa omunye futhi angase anyukele ezingeni elibucayi lokuvusa imizwa okungenzeka kube inkinga ezimeni zempilo yengqondo," kusho uWoolmer.

Ehlangene nabacwaningi baseHannover Medical School eJalimane, u-Wollmer nethimba lakhe baqala ukwakha ocwaningweni lwangaphambili lokujova i-Botox endaweni ye-glabella, indawo yobuso ngaphezu kwekhala naphakathi kwamashiya, evame ukubonisa ukucindezeleka komuntu. lapho ubhekene nemizwa engemihle.

“Uma izicubu zobuso sezicushiwe ukuze ziveze imizwa, kukhiqizwa isignali yokuvuselela umzimba, ebuya ebusweni iye ebuchosheni bomzwelo futhi iqinise futhi igcine lesi simo somzwelo,” kuchaza u-Woolmer. Kungokubonakaliswa kwale mizwa kuphela lapho umuntu eyizwa ngempela njengemizwa efudumele negcwele, noma lapho lesimo samuntu sesicindezelwe, imizwa iyadamba futhi ayibonwa kanjalo.”

I-borderline personality disorder

Ngokuphumuza imisipha yosizi, abacwaningi bafuna ukuthwebula okwenzeka ebuchosheni lapho i-loop yempendulo enhle iphukile, ngakho bahlola iziguli ze-45 ezine-borderline personality disorder (BPD), enye yezinkinga zobuntu ezivame kakhulu.

Ithimba labacwaningi lichaze ukuthi iziguli ezine-BPD zihlushwa "imizwelo emibi ngokweqile", kuhlanganise nentukuthelo nokwesaba. UWollmer uthe iziguli ze-BPD "ngomqondo othile, ziyisibonelo sokukhungatheka kaningi ngenxa yemizwa engemihle ezingakwazi ukuyilawula ngempela." Khona-ke abanye babahlanganyeli bocwaningo bathola imijovo ye-Botox, kuyilapho iqembu elilawulayo lathola i-acupuncture.

I-imaging ye-magnetic resonance yobuchopho

Ngaphambi kokwelashwa kanye namasonto amane kamuva, ababambiqhaza banikezwa umsebenzi obizwa ngokuthi "ukuhamba/ukungahambeki", lapho kwakudingeka balawule ukusabela kwabo ezicini ezithile ngenkathi bebona izithombe zobuso obunezimo ezihlukene zemizwa, kuyilapho abacwaningi. baskena ubuchopho babo besebenzisa i-imaging magnetic resonance esebenzayo. Ukuhlolwa kwaveza imiphumela exubile, kokubili iziguli ze-Botox ne-acupuncture ezibonisa ukuthuthukiswa okufanayo ngemva kokwelashwa, kodwa ithimba labacwaningi lagqugquzelwa eminye imiphumela emibili.

Ngokuhlola i-MRI, kwatholakala okokuqala ukuthi imijovo ye-Botox iguqula kanjani izici ze-neurobiological ze-BPD, njengoba izithombe ze-MRI zibonise ukuncipha komsebenzi ku-amygdala yobuchopho ekuphenduleni izisusa ezingokomzwelo.

"Sithole umphumela wokuzola ku-amygdala, ehileleke ngokujulile ekucubunguleni imizwelo engalungile futhi isebenza ngokweqile ezigulini ze-BDD," kusho u-Wollmer, enezela ukuthi umphumela ofanayo awuzange ubonakale eqenjini lokulawula eliphathwa nge-acupuncture.

Abacwaningi baphinde baphawula ukuthi imijovo ye-Botox yehlisa ukuziphatha kokuxhamazela kweziguli ngesikhathi somsebenzi "wokuhamba/ungahambi", futhi yahlotshaniswa nokusebenza kwezifunda ze-lobe yangaphambili yobuchopho ezibandakanyeka ekulawuleni okuvimbayo.

Ukwelashwa kwe-Botox yokucindezeleka

Ucwaningo lwangaphambilini lubheke ukuthi imijovo ye-Botox ingaphula kanjani izihibe zempendulo kwezinye izindawo zobuso nomzimba.

Ukuhlaziywa kwe-meta ka-2021 okuhlola idatha evela ezigulini ezingama-40 ezijovwe nge-Botox kusizindalwazi se-US Food and Drug Administration kwathola ukuthi ukuphazamiseka kokukhathazeka bekungamaphesenti angama-22 kuye kwangama-72 ngaphansi kuneziguli ezithole ezinye izindlela zokwelapha izimo ezifanayo. Ucwaningo olufanayo lwenziwa ngo-2020 ngemiphumela ecindezelayo yemijovo yeBotox, eyakhombisa ukuthi ingasetshenziswa ukwelapha ukudangala kanye nokukuvimba.

UWollmer uthe izindlela zokwelapha ezisungulwe kahle ezinjengokwelashwa kwengqondo noma ama-antidepressants azisebenzi kahle ngokwanele cishe ingxenye yesithathu yeziguli ezinokucindezeleka, “ngakho-ke, kunesidingo sokuthuthukisa izindlela zokwelapha ezintsha, futhi lapha imijovo yeBotox ingaba nendima,” echaza. ithemba lakhe kanye nethimba lakhe labacwaningi ukubona imiphumela. , okuye kwaphenywa ngokuqhubekayo ocwaningweni olukhudlwana lweSigaba XNUMX somtholampilo, lapho abacwaningi bezobona ukuthi noma yiziphi ezinye izimo zempilo yengqondo zingelashwa ngomjovo we-Botox.