Ingabe isayensi izosisindisa ephusheni elibi lokuguga?

Ingabe isayensi izosisindisa ephusheni elibi lokuguga?

Iminyaka iyahamba futhi izimpawu zokuguga ziqala ukubonakala kithi. Ayikho iminyaka yokubalekela. Kusukela ngo-2015, sibone ukukhuphuka kwesayensi okuseqophelweni eliphezulu nokungakaze kubonwe maqondana namathebulethi alwa nokuguga futhi ehlise ijubane lakho.

Kokusha, ngokwalokho okwanyatheliswa kuyi-Journal of Scientific Reports, ecaphuna ucwaningo olwenziwa yi-University of Leicester, eNgilandi, ososayensi bakwazi ukuthuthukisa ukusebenza kahle nokuphepha kwezidakamizwa “ezihlaziya ukuguga” ukuze zelaphe amasosha omzimba ngokunemba okuvumela ukuze baqondise amaseli angasebenzi kahle ngaphandle kokulimaza amaseli anempilo.

Amandla amakhulu okwelapha okulwa nokuguga aphinde alele ekhonweni layo lokukhomba lokho okwaziwa ngokuthi amaseli e-senescent, okungukuthi, lawo alahlekelwe amandla awo okuhlukanisa nokuqoqa emzimbeni futhi asheshise inqubo yokuguga.

Nakuba ukunqwabelana kwamangqamuzana ezinzwa kuyingxenye evamile yenqubo yokuguga, ososayensi benze izinyathelo ezijabulisayo zokususa la mangqamuzana emzimbeni besebenzisa imithi eyenziwe ngenjongo.

"Isikhathi Esinempilo"

Izidakamizwa ze-Geriatric ziye zaboniswa ukuthi zivuselela amangqamuzana amadala kumagundane futhi andise ubude bawo bokuphila, kuyilapho inqubekelaphambili ethembisayo yenziwe futhi ekusetshenzisweni kwawo ukuze kuthuthukiswe lokho okwaziwa ngokuthi ukuphila okunempilo.

Futhi ngenyanga edlule ibone isethulo esiyimodeli emangazayo, lapho ososayensi babonisa ukuthi izidakamizwa "ze-geriatric" zingasusa kanjani amangqamuzana aguga emigogodleni yezilwane (ezihloliwe) ezikhulile futhi zidale indawo yamangqamuzana amasha, anempilo ukuze aphumelele, okwandisa amathuba okuba nentsha entsha. ukwelashwa kobuhlungu beqolo.okungapheli kubantu.

ukudubula okungahleliwe

Ithimba lamazwe omhlaba lososayensi ngemuva kwalolu cwaningo lwakamuva liphinde liqondise lokho abakubona njengephutha esizukulwaneni samanje sezidakamizwa "ezihlaziya ukuguga", njengoba bethi bathatha indlela yokudubula izinhlamvu ezingahleliwe eziqhumeni ezidinga ukunemba okwengeziwe nokukhetha, ngokusho kombiko. incazelo yabo.

USalvador McCabe, umphenyi oyinhloko wocwaningo lwe-University of Leicester, wathi: “Imithi ye-gerolysis iyisigaba esisha semithi enamandla amakhulu okudambisa izimpawu zokuguga. Kodwa kunemiphumela engemihle eqinile kuze kube manje, futhi ngaleyo ndlela igqamisa ukubaluleka kwesizukulwane sesibili semithi elwa nokuguga, eqondise amangqamuzana aguga ngaphandle kokuthinta amanye amangqamuzana.”

Le ntuthuko engakaze ibonwe yakha ocwaningweni lwangaphambilini olwenziwa yithimba lososayensi baseNyuvesi yaseLeicester, elahlonza umaka welwelwesi lwamangqamuzana ezinzwa futhi labonisa ukuthi angaqondiswa kanjani ukuwaqeda ngezinga eliphezulu lokunemba, okwenza kube nokwenzeka ukuthuthukisa inhlanganisela entsha ye-senescent. i-antibody egcwele izidakamizwa ze-cytotoxic. , futhi ikuhlole kumasiko amaseli elabhorethri.

imiphumela ethembisayo

Ukwengeza, ukuhlola okukhethiwe kobufakazi bomqondo kuye kwabuyisela imiphumela ethembisayo, lapho umphumela ohlangene wamasosha omzimba nezidakamizwa ufana "nebhomu elihlakaniphile", amangqamuzana asebekhulile ahlonzwa futhi aqedwe izidakamizwa ezinobuthi ukuze azikhiphe ku-equation.

Ososayensi baqinisekisile ukuthi ukwelashwa akubanga nomthelela kumaseli angenayo i-senescent, okunomthelela omuhle ekunembeni nasekuphepheni kokwelashwa.

Indlela yomqondo yokwelashwa komdlavuza

"Ngokukopisha umbono osuvele usetshenziswa ekwelapheni umdlavuza, i-antibody ishintshiwe ukuze ikwazi ukubona la maseli futhi ilethe ubuthi obungaphakathi kuwo," kusho uMcCabe.

Ososayensi bathi le ndlela yintsha ngokuphelele yokuqeda amangqamuzana aguga, baveza ukuthi banethemba lokuphinda le mpumelelo nabantu ngelinye ilanga, begcizelela ukuthi bazosebenzisa le miphumela njengesisekelo sokucwaninga okwengeziwe ekwelapheni okuhloswe kakhulu kokuguga.

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